Case report
28-year-old woman (G1P0) with unremarcable medical history presented to our office at 12 weeks and 3 days of pregnancy. Our ultrasonographic examination revealed following cranial findings:
- enlarged thickness of the brainstem (BS) in sagittal planes;
- decreased size of the intracranial lucency (fourth ventricle) and cisterna magna (brainstem-occipital bone distance - BSOB distance).
The findings were suspected of spinal defect [1, 2, 3]. Repeated scan at 15 weeks and 3 days had confirmed opened lumbosacral spina bifida with classical cranial findings and pregnancy has been terminated.
患者28岁，G1P0，既往无明显病史，孕12周+3来我处就诊。超声检查所见如下：
-胎儿矢状面显示脑干（BS）增大增厚
-颅内透明层（第四脑室）和小脑延髓池（脑干-枕骨间距，BSOB）腔隙变小
根据这些表现，考虑为脊柱病变。孕15周+3时再次复查，颅内表现更为典型，确诊为开放性腰骶部脊柱裂。患者决定终止妊娠。
Images 1, 2, 3, 4, and videos 1, 2, 3: 12 weeks and 3 days of gestation.
图1-4和视频1-3：妊娠12周+3时超声表现



Images 5, 6: The image 5 shows abnormal findings that were seen in our case - increased size of the brainstem, decreased size of intracranial lucency together with compression of cisterna magna (decreased brainstem-occipital bone distance). For comparison normal findings are shown in the image 6 (for more information read articles stated in references).
图5显示脑干增大，颅内透明层和小脑延髓池变小；图6为对照的正常表现。Th：丘脑；BS：脑干；IT：颅内透明层；CM：小脑延髓池；NT：颈项透明层；BSOB：脑干-枕骨间距；Choroid plexus：脉络丛；Occipital bone：枕骨


Images 7, 8, 9, 10, 11, and videos 4, 5: 15+3 weeks - 2D and 3D images and videos showing classical signs of lumbosacral spina bifida.
图7-11和视频4-5：二维和三维图像以及动态视频显示腰骶部脊柱裂的典型表现